Many People have been having problems with Sandboxie due to the new patches. This guide will explain how to fix this problem.
Open a Sandboxied Launcher
Now on your desktop look at the bottom right
Click the up arrow and find the sandboxie Icon
Right-Click it and hover over the Box you use (ex. Default Box
Now Click on the option that says "Delete Contents"
Now another window should pop up when it is done searching the files Click on Delete contents or whatever it says on the bottom of the window
Then try to reopen the launcher through sandboxie and it should work properly now.
If that does not work then open your C: drive and delete the sandboxie folder which is located there. This should 99% of the time solve the problem.
*Pictures*
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Mandoscream was the one who told me the fix c: